Expertise Term: intramembrane proteolysis
 NameInstitutionRole
DeMartino, GeorgeThe University of Texas Southwestern Medical CenterAssociate Editor
 
 
Name: DeMartino, George
Role: Associate Editor
Email: gdemartino@asbmb.org
Institution: The University of Texas Southwestern Medical Center
Department: Physiology
Subject Categories: Metabolism
Expertise Terms: aggresome, ATP-dependent protease, ATPases associated with diverse cellular activities (AAA), autophagy, calpain, E3 ubiquitin ligase, enzyme degradation, intramembrane proteolysis, protease, proteasome, protein degradation, protein turnover, proteolytic enzyme, ubiquitin, ubiquitin ligase, ubiquitylation (ubiquitination)
Fraser, PaulUniversity of TorontoAssociate Editor
 
 
Name: Fraser, Paul
Role: Associate Editor
Email: pfraser@asbmb.org
Institution: University of Toronto
Department:
Subject Categories: Cell Biology, Molecular Bases of Disease, Neurobiology, Protein Structure and Folding
Expertise Terms: Alzheimer disease, amyloid, intramembrane proteolysis, membrane protein, neurodegeneration, neurological disease, Parkinson disease, peptide interaction, Presenilin, prion, proteasome, rhomboid protease, secretase, sumoylation, synuclein
Ha, YaYale School of MedicineEditorial Board Member
 
 
Name: Ha, Ya
Role: Editorial Board Member
Email: ya.ha@yale.edu
Institution: Yale School of Medicine
Department: Pharmacology
Subject Categories: Enzymology, Protein Structure and Folding
Expertise Terms: allosteric regulation, anticancer drug, conformational change, drug design, drug discovery, enzyme catalysis, enzyme inhibitor, enzyme structure, hydrolase, inositol phosphate, intramembrane proteolysis, membrane enzyme, membrane protein, pharmacology, phosphatidylinositol kinase (PI Kinase), Presenilin, protease, protein kinase, protein structure, rhomboid protease, structural biology, structure-function, substrate specificity, transmembrane domain, X-ray crystallography
Hrycyna, ChristinePurdue UniversityEditorial Board Member
 
 
Name: Hrycyna, Christine
Role: Editorial Board Member
Email: hrycyna@purdue.edu
Institution: Purdue University
Department: Department of Chemistry
Subject Categories: Enzymology, Lipids, Membrane Biology
Expertise Terms: ABC transporter, blood-brain barrier, enzyme inhibitor, enzyme purification, GTPase Kras (KRAS), intracellular processing, intramembrane proteolysis, isoprenoid, lamin, membrane enzyme, membrane protein, membrane transport, membrane transporter reconstitution, methyltransferase, multidrug transporter, mutagenesis, photoaffinity labeling, post-translational modification (PTM), protein methylation, protein palmitoylation, protein purification, proteolytic enzyme, recombinant protein expression, S-adenosylmethionine (SAM), transmembrane domain
Lemberg, MariusHeidelberg UniversityEditorial Board Member
 
 
Name: Lemberg, Marius
Role: Editorial Board Member
Email: m.lemberg@zmbh.uni-heidelberg.de
Institution: Heidelberg University
Department:
Subject Categories: Cell Biology, Membrane Biology, Protein Synthesis and Degradation
Expertise Terms: Cell Biology, endoplasmic reticulum (ER), endoplasmic reticulum stress (ER stress), endoplasmic-reticulum-associated protein degradation (ERAD), ER quality control, ER-associated degradation, gamma-secretase, intramembrane proteolysis, membrane protein, mitochondria, neurodegenerative disease, parkin, PARL, PINK1, protease, protein degradation, proteolysis, rhomboid protease, signal peptidase, signal peptide peptidase, ubiquitin, unfolded protein response (UPR), X-box binding protein 1 (XBP1)
Mallampalli, RamaThe Ohio State UniversityEditorial Board Member
 
 
Name: Mallampalli, Rama
Role: Editorial Board Member
Email: rama.mallampalli2@osumc.edu
Institution: The Ohio State University
Department: Internal Medicine
Subject Categories: Cell Biology, Lipids, Protein Synthesis and Degradation
Expertise Terms: epithelial cell, Hypoxia, INTRACELLULAR SIGNAL TRANSDUCTION/Sphingolipids, intramembrane proteolysis, lipid synthesis, LIPID/Phospholipid/Phosphatidylcholine, lipogenesis, lung, membrane lipid, phosphatidylcholine, phospholipid, phospholipid metabolism, phospholipid turnover, protein degradation, protein drug interaction, pulmonary surfactant, respiration, sphingolipid, ubiquitin, ubiquitin ligase
Pomerantz, JoelJohns Hopkins Univ. Sch. of MedicineEditorial Board Member
 
 
Name: Pomerantz, Joel
Role: Editorial Board Member
Email: joel.pomerantz@jhmi.edu
Institution: Johns Hopkins Univ. Sch. of Medicine
Department:
Subject Categories: Gene Regulation, Immunology, Signal Transduction
Expertise Terms: Antigen receptor signaling, B cell lymphoma, Bcl10, CARD11, IKK complex, immunodeficiency, intramembrane proteolysis, K63-linked ubiquitin, leukemia, lymphoma, MAGUK proteins, MALT1, natural killer cells (NK cells), NF-kappa B (NF-KB), scaffold protein, Signal Transduction, T-cell receptor (TCR), Transcription, tumor cell biology, ubiquitin ligase
Steiner, HaraldLudwig-Maximilians-UniversityEditorial Board Member
 
 
Name: Steiner, Harald
Role: Editorial Board Member
Email: harald.steiner@med.uni-muenchen.de
Institution: Ludwig-Maximilians-University
Department:
Subject Categories: Molecular Bases of Disease, Protein Synthesis and Degradation
Expertise Terms: Alzheimer disease, amyloid, amyloid precursor protein (APP), APH-1, APP processing, aspartic protease, drug discovery, Familial Alzheimer´s disease mutations, gamma-secretase, gamma-secretase inhibitors, Gamma-secretase modulators, intramembrane proteolysis, membrane protein, neurodegenerative disease, Nicastrin, PEN-2, Presenilin, protease, protein complex, proteolytic enzyme, rhomboid protease, secretase, signal peptide peptidase, site-directed mutagenesis, SPPLs
Talmage, DavidNIHEditorial Board Member
 
 
Name: Talmage, David
Role: Editorial Board Member
Email: david.talmage@nih.gov
Institution: NIH
Department: National Institute for Mental Health (NIMH)
Subject Categories: Molecular Bases of Disease, Neurobiology, Signal Transduction
Expertise Terms: cell signaling, central nervous system (CNS), cholinergic receptor, development, dorsal root ganglia, epidermal growth factor receptor (EGFR), erbB receptors, growth factor, intramembrane proteolysis, molecular cell biology, Neuregulin, neurite outgrowth, neurodevelopment, neurotrophic factor, neurotrophin, nicotinic acetylcholine receptors (nAChR), phosphatidylinositide 3-kinase (PI 3-kinase), receptor tyrosine kinase, schizophrenia, Signal Transduction
Tomita, TaisukeThe University of TokyoEditorial Board Member
 
 
Name: Tomita, Taisuke
Role: Editorial Board Member
Email: taisuke@mol.f.u-tokyo.ac.jp
Institution: The University of Tokyo
Department: Graduate School of Pharmaceutical Sciences, Laboratory of Neuropathology and Neuroscience
Subject Categories: Enzymology, Molecular Bases of Disease, Neurobiology
Expertise Terms: ADAMTS, Alzheimer disease, amyloid, amyloid precursor protein (APP), aspartic protease, cell adhesion, intracellular trafficking, intramembrane proteolysis, matrix metalloproteinase (MMP), membrane trafficking, metalloprotease, Notch protein, Notch receptor, Presenilin, protease inhibitor, secretase, shedding, synapse
Vooijs, MarcMAASTRICHT UNIVERSITYEditorial Board Member
 
 
Name: Vooijs, Marc
Role: Editorial Board Member
Email: marc.vooijs@maastrichtuniversity.nl
Institution: MAASTRICHT UNIVERSITY
Department: Radiotherapy
Subject Categories: Cell Biology, Molecular Bases of Disease, Signal Transduction
Expertise Terms: ADAM10, autophagy, brain tumor, cancer biology, cancer stem cells, cancer therapy, epidermal growth factor receptor (EGFR), gamma-secretase, glioblastoma, glioma, HIF, Hypoxia, hypoxia-inducible factor (HIF), intramembrane proteolysis, lung cancer, Notch, Notch pathway, Notch protein, Notch receptor, Presenilin, radiotherapy, secretase, stem cells
Weggen, SaschaHeinrich-Heine-University DuesseldorfEditorial Board Member
 
 
Name: Weggen, Sascha
Role: Editorial Board Member
Email: sweggen@uni-duesseldorf.de
Institution: Heinrich-Heine-University Duesseldorf
Department: Department of Neuropathology
Subject Categories: Cell Biology, Molecular Bases of Disease, Neurobiology
Expertise Terms: Alzheimer disease, amyloid precursor protein (APP), amyloid-beta (AB), drug development, drug discovery, Familial Alzheimer Disease, gamma-secretase, Gamma-secretase modulators, intramembrane proteolysis, membrane protein, microglia, molecular cell biology, neurodegenerative disease, neurological disease, Presenilin, Progranulin, rhomboid protease, secretase
Zhou, PeiDuke UniversityEditorial Board Member
 
 
Name: Zhou, Pei
Role: Editorial Board Member
Email: peizhou@biochem.duke.edu
Institution: Duke University
Department: Department of Biochemistry
Subject Categories: Lipids, Microbiology, Protein Structure and Folding
Expertise Terms: antibiotic action, cell metabolism, DNA damage, DNA damage response, DNA repair, intramembrane proteolysis, isothermal titration calorimetry (ITC), membrane protein, RNA polymerase II, secretase, shedding, Src homology 2 domain (SH2 domain), Src homology 3 domain (SH3 domain), surface plasmon resonance (SPR), ubiquitin, ubiquitin ligase, ubiquitin-conjugating enzyme (E2 enzyme), ubiquitin-dependent protease, unfolded protein response (UPR)