Expertise Term: drug discovery
 NameInstitutionRole
Ben Mamoun, ChoukriYale University School of MedicineEditorial Board Member
 
 
Name: Ben Mamoun, Choukri
Role: Editorial Board Member
Email: choukri.benmamoun@yale.edu
Institution: Yale University School of Medicine
Department: Medicine
Subject Categories: Lipids, Metabolism, Microbiology
Expertise Terms: drug action, drug discovery, drug resistance, genomics, lipid metabolism, malaria, membrane biogenesis, membrane lipid, membrane protein, Metabolism, Microbiology, parasite metabolism, plasma membrane, purine, translation elongation factor
Ben-Tal, NirTel-Aviv UniversityEditorial Board Member
 
 
Name: Ben-Tal, Nir
Role: Editorial Board Member
Email: bental@ashtoret.tau.ac.il
Institution: Tel-Aviv University
Department:
Subject Categories: Computational Biology, Membrane Biology, Protein Structure and Folding
Expertise Terms: ABC transporter, bioinformatics, Biophysics, Computational Biology, copper transport, drug discovery, evolutionary conservation, homology modeling, membrane protein, membrane proteins, membrane transport, molecular evolution, molecular modeling, multidrug transporter, structural biology, structural model, structure prediction, structure-function, thermodynamics, transmembrane domain, transport, transporter
Berteau, OlivierINRAEditorial Board Member
 
 
Name: Berteau, Olivier
Role: Editorial Board Member
Email: olivier.berteau@inra.fr
Institution: INRA
Department: MICALIS, ChemSyBio
Subject Categories: Enzymology, Microbiology, Protein Structure and Folding
Expertise Terms: analytical chemistry, antibiotic synthesis, antibiotics, antimicrobial peptide (AMP), bacteria, bacterial metabolism, bacterial toxin, bacteriocin, bioenergetics, bioenergy, bioengineering, biosynthesis, biotechnology, carbohydrate biosynthesis, carbohydrate metabolism, carbohydrate structure, Chemical biology, DNA repair, drug discovery, drug resistance, enzyme catalysis, enzyme degradation, enzyme inactivation, enzyme inhibitor, enzyme kinetics, enzyme mechanism, enzyme mutation, enzyme purification, enzyme structure, enzyme turnover, Escherichia coli (E. coli), iron, iron metabolism, iron sulfur, Iron-Sulfur Enzyme, iron-sulfur protein, metagenomics, metal, metal ion-protein interaction, metalloenzyme, metalloprotein, Microbiology, microbiome, natural products, peptide biosynthesis, peptides, radical adomet, Radical AdoMet enzyme, Radical SAM enzyme, RiPP, RiPPs, S-adenosylmethionine (SAM), structural biology, Sulfatase, sulfur, synthetic biology, thiol, tryptophan
Caffrey, MichaelUniversity of Illinois at ChicagoEditorial Board Member
 
 
Name: Caffrey, Michael
Role: Editorial Board Member
Email: caffrey@uic.edu
Institution: University of Illinois at Chicago
Department: Biochemistry & Molecular Genetics
Subject Categories: Membrane Biology, Molecular Biophysics, Protein Structure and Folding
Expertise Terms: Biophysics, C-C chemokine receptor type 5 (CCR5), C-X-C chemokine receptor type 4 (CXCR-4), drug discovery, drug screening, GP120, GP41, Hemagglutinin, human immunodeficiency virus (HIV), influenza, mutagenesis, nuclear magnetic resonance (NMR), protein stability, protein-protein interaction, Viral Entry, viral protein, virus assembly, virus entry, virus structure
Dovat, SinisaPennsylvania State University College of MedicineEditorial Board Member
 
 
Name: Dovat, Sinisa
Role: Editorial Board Member
Email: sdovat@hmc.psu.edu
Institution: Pennsylvania State University College of Medicine
Department:
Subject Categories: Gene Regulation, Molecular Bases of Disease, Signal Transduction
Expertise Terms: cancer biology, cell division cycle 7-related protein kinase (Cdc7), ChIP-sequencing (ChIP-seq), chromatin immunoprecipitation (ChiP), chromatin remodeling, drug discovery, Epigenetics, gene expression, gene regulation, gene transcription, hematopoiesis, histone acetylase, histone deacetylase 1 (HDAC1), histone demethylase, histone methylation, histone modification, Ikaros, leukemia, neuroblastoma, phosphoprotein phosphatase 1 (PP1), protein phosphorylation, Signal Transduction, transcription factor, transcription regulation, transcription repressor, zinc finger
Garneau-Tsodikova, SylvieUniversity of KentuckyEditorial Board Member
 
 
Name: Garneau-Tsodikova, Sylvie
Role: Editorial Board Member
Email: sylviegtsodikova@uky.edu
Institution: University of Kentucky
Department: Department of Pharmaceutical Sciences
Subject Categories: Enzymology, Microbiology, Protein Structure and Folding
Expertise Terms: acetyl-CoA synthetase, acetylcholinesterase (AChE), acetyltransferase, acyl carrier protein (ACP), acyltransferase, amyloid-beta (AB), Antibacterials, antibiotic action, antibiotic resistance, Antifungals, antimicrobial peptide (AMP), bacteria, bacterial pathogenesis, bacteriocin, biofilm, biosynthesis, carbohydrate chemistry, crystal structure, drug discovery, drug resistance, galactosyltransferase, histone acetylation, microbial pathogenesis, Mycobacterium tuberculosis, natural products, Nonribosomal peptides, Polyketides, Resistance, tuberculosis
Ha, YaYale School of MedicineEditorial Board Member
 
 
Name: Ha, Ya
Role: Editorial Board Member
Email: ya.ha@yale.edu
Institution: Yale School of Medicine
Department: Pharmacology
Subject Categories: Enzymology, Protein Structure and Folding
Expertise Terms: allosteric regulation, anticancer drug, conformational change, drug design, drug discovery, enzyme catalysis, enzyme inhibitor, enzyme structure, hydrolase, inositol phosphate, intramembrane proteolysis, membrane enzyme, membrane protein, pharmacology, phosphatidylinositol kinase (PI Kinase), Presenilin, protease, protein kinase, protein structure, rhomboid protease, structural biology, structure-function, substrate specificity, transmembrane domain, X-ray crystallography
Hardy, JeanneUniversity of Massachusetts AmherstEditorial Board Member
 
 
Name: Hardy, Jeanne
Role: Editorial Board Member
Email: hardy@chem.umass.edu
Institution: University of Massachusetts Amherst
Department: Department of Chemistry
Subject Categories: Enzymology, Molecular Bases of Disease, Protein Structure and Folding
Expertise Terms: apoptosis, Biophysics, caspase, crystallography, dengue virus (DENV), drug design, drug discovery, enzyme inactivation, enzyme inhibitor, enzyme purification, enzyme structure, ENZYMES/Peptidases, ENZYMES/Proteolytic, ENZYMES/Structure, flavivirus, hydrogen-deuterium exchange, PEPTIDES/Biosynthesis, PEPTIDES/Conformation, protease, PROTEASE/Inhibitor, PROTEASES/Caspase, PROTEASES/Death protease, PROTEIN/Allosteric, PROTEIN/Disulfide, zinc
Holz, GeorgeSUNY Upstate Medical UniversityEditorial Board Member
 
 
Name: Holz, George
Role: Editorial Board Member
Email: holzg@upstate.edu
Institution: SUNY Upstate Medical University
Department: Medicine and Pharmacology
Subject Categories: Cell Biology, Molecular Bases of Disease, Signal Transduction
Expertise Terms: beta cell (B-cell), calcium, calcium channel, calcium intracellular release, cyclic AMP (cAMP), diabetes, drug discovery, drug screening, exocytosis, G protein-coupled receptor (GPCR), glucagon, glucagon-like peptide-1, guanine nucleotide exchange factor (GEF), heterotrimeric G protein, incretin hormones, insulin secretion, ion channel, pancreatic islet, pharmacology
Hook, VivianUniv. of Calif., San DiegoEditorial Board Member
 
 
Name: Hook, Vivian
Role: Editorial Board Member
Email: vhook@ucsd.edu
Institution: Univ. of Calif., San Diego
Department:
Subject Categories: Molecular Bases of Disease, Neurobiology, Protein Synthesis and Degradation
Expertise Terms: Alzheimer disease, amyloid precursor protein (APP), amyloid-beta (AB), cathepsin B (CTSB), cysteine protease, drug discovery, Huntington disease, neurochemistry, neurodegenerative disease, neurological disease, neuropeptide, neurotransmitter release, protease, protease inhibitor, protein degradation, protein processing, proteolysis, secretase, secretion, synapse, vesicles
Kazantsev, AlekseyMass General Hospital/Harvard Medical SchoolEditorial Board Member
 
 
Name: Kazantsev, Aleksey
Role: Editorial Board Member
Email: akazantsev47@gmail.com
Institution: Mass General Hospital/Harvard Medical School
Department: Neurology
Subject Categories: Molecular Bases of Disease, Neurobiology
Expertise Terms: aging, Alzheimer disease, amyloid, amyotrophic lateral sclerosis (ALS) (Lou Gehrig disease), Chemical biology, cholesterol regulation, drug discovery, drug screening, Epigenetics, high-throughput screening (HTS), histone deacetylase (HDAC), histone deacetylase inhibitor (HDAC inhibitor) (HDI), Huntington disease, microtubule, neurodegeneration, neuroprotection, Nuclear factor 2 (erythroid-derived 2-like factor) (NFE2L2) (Nrf2), Parkinson disease, polyglutamine disease, protein aggregation, protein misfolding, sirtuin, small molecule, tubulin
Kvaratskhelia, MamukaUniversity of Colorado School of MedicineEditorial Board Member
 
 
Name: Kvaratskhelia, Mamuka
Role: Editorial Board Member
Email: mamuka.kvaratskhelia@ucdenver.edu
Institution: University of Colorado School of Medicine
Department: Division of Infectious Diseases
Subject Categories: DNA and Chromosomes, Molecular Bases of Disease, Protein Structure and Folding
Expertise Terms: Akt PKB, allosteric inhibitors, allosteric regulation, chromatin, DNA binding protein, DNA damage, DNA repair, DNA-protein interaction, drug discovery, drug resistance, drug screening, gene expression, HIV-1 protease, host-pathogen interaction, human immunodeficiency virus (HIV), infectious disease, integrase, lentivirus, mass spectrometry (MS), medicinal chemistry, nucleus, PDZ domain, phosphatase, phosphatase and tensin homolog (PTEN), protein-DNA interaction, protein-protein interaction, retroviral integrase
Saarma, MartInstitute of Biotechnology, HiLIFE, Helsinki UniversityEditorial Board Member
 
 
Name: Saarma, Mart
Role: Editorial Board Member
Email: mart.saarma@helsinki.fi
Institution: Institute of Biotechnology, HiLIFE, Helsinki University
Department:
Subject Categories: Molecular Bases of Disease, Neurobiology
Expertise Terms: Alzheimer disease, cell death, drug discovery, N-cadherin, Neurobiology, neurochemistry, neurodegenerative disease, neurological disease, neuropeptide, neuroprotection, neuroscience, neurotrophic factor, neurotrophin, oxidative stress, Parkinson disease, stroke
Safe, StephenTexas A&M UniversityEditorial Board Member
 
 
Name: Safe, Stephen
Role: Editorial Board Member
Email: ssafe@cvm.tamu.edu
Institution: Texas A&M University
Department: Veterinary Physiology & Pharmacology
Subject Categories: Gene Regulation, Signal Transduction
Expertise Terms: anticancer drug, breast cancer, C-X-C chemokine receptor type 4 (CXCR-4), cancer, cancer biology, cancer chemoprevention, cannabinoid receptor, colon cancer, colorectal cancer, cytochrome P450, dioxin, drug development, drug discovery, ER stress, estrogen, estrogen receptor, gastric cancer, histone methylation, Kruppel-like factor (KLF), liver cancer, molecular endocrinology, molecular oncology, nuclear receptor, reactive oxygen species (ROS), specificity protein 1 (Sp1), tumor cell biology, tumor therapy
Seifert, RolandMedical School of HannoverEditorial Board Member
 
 
Name: Seifert, Roland
Role: Editorial Board Member
Email: seifert.roland@mh-hannover.de
Institution: Medical School of Hannover
Department: Pharmacology
Subject Categories: Cell Biology, Immunology, Signal Transduction
Expertise Terms: adenylate cyclase (adenylyl cyclase), adrenergic receptor, anthrax toxin, Bordetella pertussis, Chemical biology, cyclic AMP (cAMP), cyclic GMP (cGMP), cyclic nucleotide, drug discovery, G protein, G protein-coupled receptor (GPCR), leukocyte, molecular pharmacology, myeloid cell, neutrophil, nucleoside/nucleotide analogue, nucleoside/nucleotide metabolism, nucleoside/nucleotide transport, nucleotide, pharmacology, phosphodiesterases, protein kinase A (PKA), protein kinase G (PKG), second messenger, Signal Transduction
Sobrado, PabloVirginia TechEditorial Board Member
 
 
Name: Sobrado, Pablo
Role: Editorial Board Member
Email: psobrado@vt.edu
Institution: Virginia Tech
Department: Biochemistry
Subject Categories: Enzymology, Glycobiology and Extracellular Matrices, Molecular Biophysics
Expertise Terms: drug discovery, electron transfer, enzyme catalysis, enzyme kinetics, enzyme mechanism, enzyme purification, flavin, galactofuranose, inhibitor, isotope effect, kinetics, pre-steady-state kinetics, protein chemistry, protein structure, siderophore
Steiner, HaraldLudwig-Maximilians-UniversityEditorial Board Member
 
 
Name: Steiner, Harald
Role: Editorial Board Member
Email: harald.steiner@med.uni-muenchen.de
Institution: Ludwig-Maximilians-University
Department:
Subject Categories: Molecular Bases of Disease, Protein Synthesis and Degradation
Expertise Terms: Alzheimer disease, amyloid, amyloid precursor protein (APP), APH-1, APP processing, aspartic protease, drug discovery, Familial Alzheimer´s disease mutations, gamma-secretase, gamma-secretase inhibitors, Gamma-secretase modulators, intramembrane proteolysis, membrane protein, neurodegenerative disease, Nicastrin, PEN-2, Presenilin, protease, protein complex, proteolytic enzyme, rhomboid protease, secretase, signal peptide peptidase, site-directed mutagenesis, SPPLs
Ulens, ChrisKU LeuvenEditorial Board Member
 
 
Name: Ulens, Chris
Role: Editorial Board Member
Email: chris.ulens@kuleuven.be
Institution: KU Leuven
Department: Cellular and Molecular Medicine
Subject Categories: Molecular Biophysics, Neurobiology, Protein Structure and Folding
Expertise Terms: Biophysics, channel activation, crystal structure, crystallography, cyclic AMP (cAMP), cyclic nucleotide-gated (CNG) channel, Cys-loop receptor, drug discovery, GABA receptor, glycine receptor, hERG, hyperpolarization-activated cyclic nucleotide sensitive (HCN) channel, ion channel, membrane protein, Neurobiology, nicotinic acetylcholine receptors (nAChR), pentameric ligand-gated ion channel, pharmacology, potassium channel, protein crystallization, serotonin, sodium channel, transient receptor potential channels (TRP channels), X-ray crystallography
Weggen, SaschaHeinrich-Heine-University DuesseldorfEditorial Board Member
 
 
Name: Weggen, Sascha
Role: Editorial Board Member
Email: sweggen@uni-duesseldorf.de
Institution: Heinrich-Heine-University Duesseldorf
Department: Department of Neuropathology
Subject Categories: Cell Biology, Molecular Bases of Disease, Neurobiology
Expertise Terms: Alzheimer disease, amyloid precursor protein (APP), amyloid-beta (AB), drug development, drug discovery, Familial Alzheimer Disease, gamma-secretase, Gamma-secretase modulators, intramembrane proteolysis, membrane protein, microglia, molecular cell biology, neurodegenerative disease, neurological disease, Presenilin, Progranulin, rhomboid protease, secretase
Wencewicz, TimWashington UniversityEditorial Board Member
 
 
Name: Wencewicz, Tim
Role: Editorial Board Member
Email: wencewicz@wustl.edu
Institution: Washington University
Department: Chemistry
Subject Categories: Enzymology, Molecular Bases of Disease
Expertise Terms: acyl carrier protein (ACP), acyltransferase, amino acid, amino acid transport, aminoacyl tRNA synthetase, antibiotic action, antibiotic resistance, antibiotics, decarboxylase, drug action, drug delivery, drug delivery system, drug design, drug development, drug discovery, drug resistance, drug screening, drug transport, enzyme, enzyme catalysis, enzyme inactivation, enzyme inhibitor, enzyme inhibitors, enzyme kinetics, enzyme mechanism, flavin, flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN), flavoprotein, glutamine synthase, infectious disease, inhibition mechanism, inhibitor, iron, iron acquisition, iron metabolism, mechanistic enzymology, medicinal chemistry, membrane transport, metal homeostasis, natural product, natural product biosynthesis, nitrogen metabolism, organic chemistry, peptide biosynthesis, peptide chemical synthesis, peptide transport, protease inhibitor, protein chemistry, siderophore, siderophores, transport metal, xenobiotic