Expertise Term: drug metabolism
Guengerich, F.Vanderbilt University School of MedicineDeputy Editor
Name: Guengerich, F.
Role: Deputy Editor
Institution: Vanderbilt University School of Medicine
Department: Department of Biochemistry
Subject Categories: DNA and Chromosomes, Enzymology, Metabolism
Expertise Terms: crystallography, cytochrome P450, DNA damage, DNA enzyme, DNA polymerase, drug metabolism, enzyme catalysis, enzyme inhibitor, enzyme kinetics, enzyme mechanism, flavoprotein, heme, iron, mass spectrometry (MS), oxidation-reduction (redox), oxidative stress, peroxidase, protein chemistry, protein-DNA interaction, reactive oxygen species (ROS), site-directed mutagenesis, spectroscopy, sulfhydryl, xenobiotic
Hackett, JohnFlorida International UniversityEditorial Board Member
Name: Hackett, John
Role: Editorial Board Member
Institution: Florida International University
Department: Chemistry & Biochemistry
Subject Categories: Computational Biology, Enzymology, Molecular Biophysics
Expertise Terms: computation, Computational Biology, Computational Chemistry, cytochrome P450, drug action, drug metabolism, electron transfer, enzyme catalysis, enzyme kinetics, enzyme mechanism, heme, iron, kinetics, ligand-binding protein, molecular dynamics, molecular modeling, Quantum Chemistry, Raman spectroscopy, Resonance Raman Spectroscopy, spectroscopy, steroid, steroid hormone
Johnson, EricScripps ResearchEditorial Board Member
Name: Johnson, Eric
Role: Editorial Board Member
Institution: Scripps Research
Department: Molecular Medicine
Subject Categories: Enzymology, Gene Regulation, Protein Structure and Folding
Expertise Terms: aryl hydrocarbon receptor (AhR) (AHR), cytochrome P450, drug metabolism, enzyme structure, epoxygenase pathway, fatty acid omega hydroxylases, fatty acid oxidation, gene regulation, molecular docking, nuclear receptor, peroxisome proliferator-activated receptor (PPAR), protein structure, steroidogenesis, structural biology, Uridine 5'-diphospho-glucuronosyltransferase (UDP-glucuronosyltransferase), X-ray crystallography
Kensler, ThomasFred Hutchinson Cancer Research CenterEditorial Board Member
Name: Kensler, Thomas
Role: Editorial Board Member
Institution: Fred Hutchinson Cancer Research Center
Department: Translational Research Program
Subject Categories: Signal Transduction
Expertise Terms: cancer chemoprevention, cancer prevention, carcinogenesis, chemoprevention, drug metabolism, hepatocellular carcinoma, Keap1, liver cancer, liver metabolism, mycotoxin, Notch pathway, Nuclear factor 2 (erythroid-derived 2-like factor) (NFE2L2) (Nrf2), pharmacology, resveratrol, toxicology, xenobiotic
Mani, SridharAlbert Einstein College of MedicineEditorial Board Member
Name: Mani, Sridhar
Role: Editorial Board Member
Institution: Albert Einstein College of Medicine
Department: Medicine
Subject Categories: Cell Biology, Metabolism, Microbiology
Expertise Terms: 7-helix receptor, acetylation, allosteric regulation, animal model, anticancer drug, aryl hydrocarbon receptor (AhR) (AHR), autoimmunity, bacteria, bacterial metabolism, biofilm, cancer, cell metabolism, colorectal cancer, DNA binding protein, drug development, drug metabolism, Enterococcus, hepatocyte nuclear factor 4 (HNF-4), hormone receptor, indoleamine-pyrrole 2,3-dioxygenase (IDO1), inflammation, inflammatory bowel disease (IBD), innate immunity, intestinal epithelium, Intestinal inflammation and cancer, Microbial metabolites, Orphan nuclear receptors, protein drug interaction
Mattevi, AndreaUniversity of PaviaEditorial Board Member
Name: Mattevi, Andrea
Role: Editorial Board Member
Institution: University of Pavia
Department: Dept. Biology and Biotechnology
Subject Categories: Metabolism, Molecular Biophysics, Protein Structure and Folding
Expertise Terms: biocatalysis, cryo-electron microscopy, drug design, drug metabolism, enzyme inhibitor, enzyme mechanism, flavin, flavin adenine dinucleotide (FAD), histone demethylase, lipid ether, NADPH oxidase, nucleosome, oxidase, protein engineering, reactive oxygen species (ROS), structural biology, X-ray crystallography
Scott, EmilyUniversity of MichiganEditorial Board Member
Name: Scott, Emily
Role: Editorial Board Member
Institution: University of Michigan
Subject Categories: Protein Structure and Folding
Expertise Terms: cytochrome, cytochrome P450, drug metabolism, heme, metalloprotein, phase I drug metabolism, protein conformation, protein crystallization, protein drug interaction, protein expression, protein purification, recombinant protein expression, steroid hormone, steroidogenesis, structural biology, X-ray crystallography
Yarema, KevinJohns Hopkins UniversityEditorial Board Member
Name: Yarema, Kevin
Role: Editorial Board Member
Institution: Johns Hopkins University
Subject Categories: Glycobiology and Extracellular Matrices, Metabolism
Expertise Terms: analytical chemistry, antibody engineering, anticancer drug, bioengineering, biomaterials, carbohydrate biosynthesis, carbohydrate metabolism, carbohydrate processing, click chemistry, drug metabolism, glucose metabolism, glycobiology, glycosyltransferase, metabolic engineering, nanotechnology, neuraminidase, oligosaccharide, sialic acid, sialidase, sialyltransferase, sugar transport, tissue engineering, tumor metabolism, Warburg effect